Cancer-Related Dictionary

Sarcoma is a type of malignant tumor that arises from transformed cells of mesenchymal (connective tissue) origin. It can occur in various locations in the body, including the bones, muscles, tendons, cartilage, nerves, fat, and blood vessels. Despite being relatively rare, sarcomas are aggressive and often require intense treatment modalities such as surgery, radiation, and chemotherapy.

Sarcomatoid carcinoma is a rare type of cancer that exhibits both carcinoma and sarcoma characteristics. It is an aggressive tumor that can occur in various organs and tissues, often presenting challenges in diagnosis and treatment due to its mixed cellular components.

Secondary cancer, also known as metastatic cancer, occurs when cancer cells spread from the original (primary) site to another part of the body. This process involves the movement of cancer cells through the bloodstream or lymphatic system, leading to the formation of new tumors in other organs or tissues. Secondary cancers retain the name of the primary cancer type, even though they appear in a different location.

Secondary malignancies are new cancers that occur in a person who has previously been diagnosed with cancer. These are not recurrences of the original cancer but entirely new types of cancer that develop as a result of the initial cancer treatment, genetic predisposition, or other risk factors.

The semen analysis is the most important test available to evaluate male fertility. To do this, one needs to provide a semen sample. In a laboratory, a drop of semen is examined under a microscope and the number (sperm count), shape (morphology), and mobility (movement) of the sperm are determined. Sperm count: Either >16 million per ml or a total of over 39 million per ejaculation is considered normal. Shape: At least 4% must have a normal shape. The head, the midpiece, and the tail of the sperm are assessed. Mobility: More than 42% of sperm need to move and more than 30% need to travel. Movement is classified as progressive (purposeful forward movement), non-progressive (local movement, circular movement), or immotile (no movement).

A sentinel lymph node biopsy is a surgical procedure used to determine if cancer has spread beyond a primary tumor into the lymphatic system. It involves identifying, removing, and examining the sentinel lymph nodes, which are the first nodes to which cancer cells are likely to spread from a primary tumor.

Sentinel node mapping is a medical procedure used to identify the first lymph node, known as the sentinel node, that cancer cells are most likely to spread to from a primary tumor. This technique helps doctors determine the extent of cancer spread and plan appropriate treatment.

A sentinel lymph node is the first lymph node or group of nodes where cancer cells are most likely to spread from a primary tumor. Doctors commonly examine the sentinel nodes through a procedure called a sentinel lymph node biopsy to determine if cancer has started to metastasize or spread.

Serous carcinoma is a type of cancer that originates in the epithelial cells lining certain organs, most commonly the ovaries, fallopian tubes, and the peritoneum. It is characterized by the production of a thin, watery fluid and is known for its aggressive nature and rapid spread.

Sessile serrated lesions are a type of growth found in the colon that can potentially develop into cancer. They are characterized by a flat, broad base and a saw-tooth appearance under a microscope. These lesions are considered precancerous and are often detected during routine colonoscopies.

Small molecule inhibitors are a type of medication designed to block specific enzymes or proteins in cells that contribute to disease processes, such as cancer. These drugs are typically small enough to enter cells easily and interfere with the function of target molecules, helping to slow or stop the progression of diseases.

Small cell lung cancer is a fast-growing type of lung cancer usually caused by smoking. It typically starts in the bronchi, quickly spreads throughout the body, and manifests with symptoms such as cough, chest pain, and shortness of breath. Treatment options include chemotherapy, radiation therapy, and surgery. This cancer represents about 10 -15% of all lung cancers.

Soft tissue sarcoma is a rare type of cancer arising from the soft tissues like fat, muscle, nerves, fibrous tissues, blood vessels, or deep skin tissues. It can occur in any part of the body, however, it is most commonly found in the arms, legs, chest, or abdomen. Prompt diagnosis and treatment are crucial for managing this condition effectively.

Spindle cell carcinoma is a rare type of cancer characterized by spindle-shaped cells that can appear in various parts of the body, often resembling sarcomas due to their shape. It typically occurs in the skin or soft tissues and can be aggressive, requiring prompt medical attention.

Splenic lymphoma is a type of cancer that originates in the lymphatic tissue of the spleen, a vital organ involved in filtering blood and supporting the immune system. It is characterized by the uncontrolled growth of lymphocytes, a type of white blood cell.

Sporadic cancer refers to cancer that occurs by chance and is not associated with inherited genetic mutations. Most cancers are sporadic, meaning they arise from genetic changes acquired during a person's lifetime due to environmental factors or random cell mutations.

Squamous metaplasia is a process where one type of mature cell is replaced by another type of mature cell. This usually occurs as an adaptation to chronic irritation or inflammation, where glandular cells transform into squamous cells, which are more resistant to such conditions.

"Squamous cell carcinoma" is a prevalent type of skin cancer that originates from squamous cells. These cells form the outer layer of the skin's epidermis. The condition is commonly caused by prolonged exposure to ultraviolet (UV) radiation from the sun or tanning beds. It often exhibits as a firm, red nodule, or a flat lesion with a scaly, crusty surface. Though primarily appearing on sun-exposed areas, it can occur anywhere on the body. Early diagnosis and treatment are vital in preventing its spread.

"Staging" in the healthcare context, refers to the process of determining the size and spread of a specific disease or cancer within the patient's body. It facilitates the development of an appropriate treatment plan, and helps predict patient prognosis. The stage is often denoted by Roman numerals I, II, III, or IV.

A stem cell transplant, also known as a bone marrow transplant, is a medical procedure where damaged or diseased bone marrow is replaced by healthy stem cells. These cells can regenerate into new bone marrow that produces normal blood cells. This procedure may be necessary in treatment of certain cancers, blood disorders or immune deficiency syndromes.

Stereotactic radiosurgery is a non-surgical procedure that uses detailed imaging techniques and multiple streams of precise, high-energy radiation to treat tumors and other abnormalities in the brain, spine, lungs or other body parts, without harming the surrounding healthy tissue. It minimizes side effects and allows for a swift recovery.

"Steroid therapy" refers to the medical use of steroid hormones, either naturally occurring or synthetic, to treat diseases and conditions. Steroids can reduce inflammation, suppress immune system response, and balance hormones. They're used in conditions like asthma, arthritis, autoimmune diseases, and cancer. Steroid treatment must be managed carefully due to potential side effects.

A "Stoma" is a medical term referring to an artificially created opening in the body, often established during surgical procedures. It serves as a direct pathway for waste elimination from the body or breathing, mainly in cases where natural processes have been hindered due to health conditions. Typical types include colostomy, ileostomy, and tracheostomy.

Superficial spreading melanoma is a common type of skin cancer that begins in the pigment-producing cells of the skin. It typically appears as a flat or slightly raised discolored patch with irregular borders and can grow outward across the surface of the skin before penetrating deeper layers.

"Surgery" refers to the medical field that uses operative techniques to investigate or treat physical conditions. It involves cutting, ablation, suturing or otherwise physically altering body tissues and organs, frequently performed to remove or repair damaged parts. Types of surgery can range from minor procedures to complex major surgeries. It often ventures into science, art, and technology.

Surgical staging is a procedure used to determine the extent of cancer spread within the body. It involves a surgeon examining tissues, organs, and sometimes lymph nodes during surgery to assess how far the cancer has progressed. This information helps doctors plan the most effective treatment strategy.

A surgical oncologist is a specialist in the field of oncology, responsible for the surgical removal of tumors and cancerous tissues. They work as part of a multidisciplinary team, providing surgical interventions, performing biopsies, and contributing to treatment planning for cancer patients. Their expertise lies in cancer surgery and understanding tumor biology.

Survivorship care refers to the comprehensive healthcare and support provided to individuals who have completed initial cancer treatment. It focuses on monitoring for recurrence, managing long-term side effects, and addressing psychosocial needs to help survivors lead healthy lives.

Systemic therapy refers to the use of medication or treatment that affects the entire body rather than a specific area or part. It is commonly used to treat diseases that have spread throughout the body, such as cancer, by circulating through the bloodstream to reach cells in various locations.