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Long-Term Second Primary Cancer Risk in Adolescent and Young Adult (15-39 Years) Cancer Survivors: A Population-Based Study in the Netherlands Between 1989 and 2018
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Long-Term Second Primary Cancer Risk in Adolescent and Young Adult (15-39 Years) Cancer Survivors: A Population-Based Study in the Netherlands Between 1989 and 2018

Few studies have comprehensively investigated the long-term second cancer risk among adolescent and young adult (AYA, aged 15-39 years) cancer survivors. This study investigated the long-term second cancer risk by including the full range of first and second cancer combinations with at least 10 observations in the Netherlands between 1989 and 2018.

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AYA cancer survivors have a higher cancer risk compared to the general population for most cancers up to 25 years after their initial cancer diagnosis. Additional studies that investigate risk factors for the specific cancer type combinations are needed to develop personalized follow-up strategies.

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Continue reading · Late Effects of TreatmentOutcome Indicators Make Quality of Life After Pediatric Cancer MeasurableThe focus of childhood cancer treatment is to achieve a cure for all patients. With improving survival rates, the emphasis has shifted towards assessing long-term health outcomes as a measure of quality care. The International Childhood Cancer Outcome Project involved various stakeholders, including survivors, pediatric oncologists, medical, nursing, and paramedical care providers, as well as psychosocial and neurocognitive care providers. They collaborated to develop a set of core outcomes for different types of childhood cancers, allowing for outcome-based evaluation of childhood cancer care. Through surveys and online focus groups, unique candidate outcome lists were created for 17 types of childhood cancer. A two-round Delphi survey involving 435 healthcare providers from 68 institutions resulted in the selection of four to eight physical core outcomes and three aspects of quality of life per pediatric cancer subtype. These core outcomes, measured through various instruments, provide valuable information to patients, survivors, and healthcare providers, enabling assessment of institutional progress and comparisons with other facilities.

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