Try adjusting your type
14th October, 2009
European Survey on Standards of Care in paediatric oncology centres. J. R. Kowalczyk, M. Samardakiewicz, K. Pritchard-Jones, R. Ladenstein, S. Essiaf, E. Fitzgerald, G. Petrarulo, G. Vassal - EJC , Volume 61, pp 11-19
8th December, 2014
The purpose of this website is to provide good and clear information about the long-term effects of childhood cancer and to refer to the various late-effects outpatient clinics (LATER outpatient clinics) that exist in the Netherlands.
8th September, 2015
Cancer in young people is rare, but it is still a major health issue in Europe. Each year, more than 6,000 young people in Europe die of cancer. There are more than 300,000 European childhood cancer survivors (in 2020, they will be nearly half a million): two-thirds of them have some late side effects of treatment, that are severe and impact on the daily life of half of those affected.
Melanocytes are a type of skin cells found in the lower part of the epidermis, the top layer of the skin. These cells are primarily responsible for the production of melanin, the pigment that gives skin, hair, and eyes their color. Melanocytes play a crucial role in protecting skin from harmful effects of UV radiation from the sun.
The human body is a complex system, with each component playing its vital role. One such crucial component is the melanocytes present in our skin. The understanding of these melanocytes is essential as they are intrinsic to several vital functions related to our skin’s health and aesthetics.
Before delving into the specifics of melanocytes, it is crucial to grasp the basic structure of our skin. The human skin comprises three fundamental layers – the epidermis, the dermis, and the hypodermis. Each layer has a unique function and consists of various cell types, including melanocytes.
The primary role of skin cells includes protection against harmful substances, regulation of body temperature, production of Vitamin D, and also contributing to overall appearance. Among these skin cells, melanocytes hold a unique and vital responsibility.
So, what exactly are melanocytes? Melanocytes are unique cells found in the basal layer of the epidermis, the skin’s outermost layer. Apart from the skin, these cells are also present in other parts of the human body, including the eyes and the hair.
The principal role of melanocytes is to produce the pigment melanin, which is responsible for the color of our skin, hair, and eyes. Besides giving color, melanin also plays a crucial role in protecting our skin from harmful ultraviolet (UV) light, reducing the risk of skin cancer.
Interestingly, the distribution and quantity of melanocytes vary among individuals. This variation leads to the diverse skin colors observed in different races and ethnicities across the world.
In the world of human skin coloration, melanin is a crucial player. But what exactly is melanin? Melanin is a pigment produced inside the melanocytes through a process known as melanogenesis. Melanogenesis is triggered by exposure to UV light, leading to more melanin production, which in turn causes the skin to darken, commonly known as sun tan.
Melanin, however, is not just a cosmetic pigment. It has a diverse range of effects on the human body. Its primary function is to absorb UV light, protecting the skin from harmful solar radiation. It also plays a key role in visual acuity and hearing.
Like most biological systems, disruptions within melanocytes can lead to diseases and disorders. The most commonly known skin disorders related to melanocytes are hypopigmentation and hyperpigmentation, where the color of the skin becomes lighter or darker, respectively.
Besides these, the abnormal proliferation of melanocytes can lead to skin cancer, specifically melanoma. Other disorders include Vitiligo, where the loss of melanocytes leads to white patches on the skin, and Albinism, where there is a complete or near-complete lack of melanin.
The research in the field of melanocytes is of utmost importance considering the various roles these cells play. Ongoing studies aim at understanding the melanogenesis process, exploring ways to control it, and understanding the factors contributing to melanoncyte-related disorders.
Advances in melanocyte study have so far been promising. There has been an exponential increase in the use of technology for melanocyte research, leading to exciting innovations in skin disorder treatments and pigmentation management.
In conclusion, melanocytes are one of the tiny yet significant entities in our system playing a crucial role in maintaining our skin’s health and aesthetics. They are invaluable, offering protective and aesthetic value.
Despite the extensive knowledge about melanocytes, the field still opens up numerous opportunities for research. With each ensuing day, the understanding of melanocytes enlarges, taking us one step closer to taming the various disorders associated with them.
Melanocytes’ primary role is to produce melanin, the pigment responsible for the color of our skin, hair, and eyes. They also protect our skin from harmful UV light.
The distribution and quantity of melanocytes vary among individuals, resulting in diverse skin colors observed in different races and ethnicities across the world.
Disorders related to melanocytes include hypopigmentation and hyperpigmentation, skin cancer, specifically melanoma, Vitiligo, and Albinism.
Unlike other skin cells, melanocytes produce melanin, which gives color to our skin and protects it from harmful UV light.
Melanocytes produce the pigment melanin. The process of melanin production within the melanocytes is known as melanogenesis, which is triggered by exposure to UV light.
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