Try adjusting your type
14th October, 2009
European Survey on Standards of Care in paediatric oncology centres. J. R. Kowalczyk, M. Samardakiewicz, K. Pritchard-Jones, R. Ladenstein, S. Essiaf, E. Fitzgerald, G. Petrarulo, G. Vassal - EJC , Volume 61, pp 11-19
8th December, 2014
The purpose of this website is to provide good and clear information about the long-term effects of childhood cancer and to refer to the various late-effects outpatient clinics (LATER outpatient clinics) that exist in the Netherlands.
8th September, 2015
Cancer in young people is rare, but it is still a major health issue in Europe. Each year, more than 6,000 young people in Europe die of cancer. There are more than 300,000 European childhood cancer survivors (in 2020, they will be nearly half a million): two-thirds of them have some late side effects of treatment, that are severe and impact on the daily life of half of those affected.
“Cribriform” is a term used in anatomy and histology, referring to a structure that appears perforated or sieve-like. The term is frequently used to describe a structural pattern characterized by numerous round, small openings – resembling a sieve. This term is often mentioned with the cribriform plate of the ethmoid bone in the skull or in pathological processes like cribriform carcinoma.
In the vast field of healthcare, an understanding of minute body structures and functions such as the cribriform plate is of the essence. This nuanced knowledge can provide profound insight into diagnosing and treating numerous health conditions, some of which may exhibit an elusive pattern. This article delves into the comprehensive study of the cribriform plate.
With a pivotal role in the nervous system, it’s integral to understand the anatomy, pathologies related to the cribriform and its integral role within the human body. With growing advancements in medicine, the significance of the cribriform plate is gaining more attention, notably in understanding diseases and advancing diagnostic processes.
The term ‘cribriform’ is typically used in anatomy to describe perforated body structures. It is derived from the Latin root word ‘cribrum,’ meaning sieve. Such structures, like the cribriform plate, exhibit sieve-like features with multiple tiny holes.
The etymology of cribriform provides valuable insight into the structure and function of such anatomical components. It accounts for the nature of substances passing through it while implying a critical role in the body’s dynamic systems.
Located in the anterior cranial fossa of the skull, the cribriform plate is part of the ethmoid bone. It’s punctuated by many tiny foramina, which allow the olfactory nerve fibers to pass through, connecting the brain with the nasal epithelium. Its perforated, sieve-like structure facilitates the sense of smell.
The cribriform plate acts as a crucial pathway within the nervous system. Thus, any damage or alteration to this structure could impair the olfactory system or potentially open a pathway for infections to reach the brain, given its critical location.
Several conditions can affect the cribriform plate, such as congenital defects, traumatic brain injury, and inflammation caused by infections. These conditions can hinder olfactory function or even lead to ulterior health consequences like meningitis.
An in-depth look at cribriform breast cancer reveals it as a distinctive subtype of invasive breast cancer, characterized by nest-like tumor formations with perforations similar to the cribriform structure. This type underscores the need for specialized diagnostic and therapeutic strategies.
Clinical examinations regarding sense of smell, especially in instances of persistent nasal issues or following trauma, can point to potential issues with the cribriform plate. Neurological evaluations, including testing the olfactory reflexes, may also provide critical diagnostic information.
Imaging techniques such as MRI and CT scans offer further insight into potential anomalies, injuries, or tumors surrounding this area. Histopathology remains an essential diagnostic tool for determining conditions like cribriform breast cancer.
Treatment strategies for cribriform conditions vary immensely based on the nature and severity of the condition. Traditional therapeutic approaches might encompass antibiotics for combating infections or surgery to manage tumors or traumatic injuries.
Advanced therapies, including targeted pharmacotherapy or specialized surgical interventions, are used in cases like cribriform breast cancer. Prognosis varies, and long-term care typically involves regular follow-up examinations and potential adjustments in the treatment protocol.
Research into the cribriform plate and its related conditions continues to make strides. The better understanding of the genetic and molecular basis of conditions like cribriform breast cancer is shedding light on potential targeted treatments.
The future of cribriform studies holds tremendous promise, with advancements in technology and insights into the profound intricacies of the human body. It’s highly anticipated that these developments will refine diagnostic and treatment approaches further.
In conclusion, grasping the complexities of the cribriform plate can profoundly impact our understanding of multiple health conditions, their diagnostics, and management. Its pivotal role within the nervous system underscores its significance in healthcare.
Through comprehensive knowledge of cribriform, healthcare professionals are better equipped to accurately diagnose and treat numerous conditions, improving patient prognosis and quality of life.
The cribriform plate serves as a crucial passage for nerve fibers from the olfactory epithelium to the brain, facilitating the sense of smell.
Cribriform breast cancer is a distinct subtype characterized by nest-like tumor formations with perforations, resembling the cribriform structure. It calls for specific diagnostic and therapeutic approaches.
Symptoms can range from smell disturbances to severe conditions like meningitis, depending on the exact pathology affecting the cribriform plate.
Diagnosis involves clinical examination, neurological evaluation, and advanced imaging methods. Histopathological examination remains crucial in conditions like cribriform breast cancer.
Treatments options span from traditional methods like antibiotics and surgery to advanced targeted therapies, depending on the nature and severity of the condition.
Share it
You might also like
The Truth about Cancer: What You Need to Know about Cancer’s History, Treatment, and Prevention
New in paperback: the controversial bestseller from one of health care's most passionate and outspoken advocates that reveals what we need to know about cancer to protect ourselves, treat ourselves, and even save our lives.
Dying to Be Me: My Journey from Cancer, to Near Death, to True Healing
Anita Moorjani's memoir, "Dying to Be Me," is a deeply inspiring account of her extraordinary journey through illness, near-death, and profound self-discovery.
The Emperor of All Maladies: A Biography of Cancer
An award-winning exploration of cancer's intricate history and humanity's relentless fight against it. From ancient origins to modern breakthroughs, Siddhartha Mukherjee's Pulitzer Prize-winning book reveals the captivating, inspiring, and sometimes sobering tale of 'The Emperor of All Maladies.'
Radical Acceptance: Embracing Your Life With the Heart of a Buddha
Within the pages of "Radical Acceptance," readers discover a profound message: the affirmation of our complete selves. Tara Brach gently guides us to recognize and embrace every facet of our being—the light and the shadow, the joy and the sorrow.
Surviving Triple-Negative Breast Cancer: Hope, Treatment, and Recovery
After her diagnosis of hormone-negative breast cancer, health journalist Patricia Prijatel did what any reporter would do: start investigating the disease, how it occurs, how it's treated, and how to keep it from recurring.
The Resilience Factor: 7 Keys to Finding Your Inner Strength and Overcoming Life’s Hurdles
Everyone needs resilience, and now two expert psychologists share seven proven techniques for enhancing our capacity to weather even the cruelest setbacks.
Being Mortal: Medicine and What Matters in the End
Named a Best Book of the Year by The Washington Post, The New York Times Book Review, NPR, and the Chicago Tribune, "Being Mortal" is a poignant and enlightening exploration of the intersection between medicine and the inescapable realities of aging and death.
