Cancer Dictionary

Acute Lymphoblastic Leukemia (ALL) is a rare type of cancer characterized by the rapid production of abnormal white blood cells in the bone marrow. These cells impede the production of normal blood cells, triggering symptoms like fatigue, fever, and bleeding. ALL is most common in children but can also occur in adults. Treatment often involves chemotherapy, radiation, targeted therapy, or stem cell transplant.

Anal cancer is a rare type of malignancy arising from the anal canal or rectum. It starts when healthy cells in or around the anus change and grow out of control, forming a mass. Risk factors include increasing age, history of HPV infections, and smoking. Symptoms may include rectal bleeding, pain, or changes in bowel movements. Treatment often involves chemotherapy, radiation, or surgery.

Angiosarcoma is a rare, malignant tumor that originates from endothelial cells, the cells that line the interior surface of blood vessels. It can occur anywhere in the body, but is most commonly found in the skin, breast, liver, spleen, and deep tissue. Due to its aggressive nature, it often leads to a poor prognosis. This tumor presents unique challenges due to its high recurrence rate and resistance to treatment.

Breast cancer is a malignancy originating in the breast tissue, where cells begin to grow uncontrollably, forming a tumor. This tumor can potentially invade nearby tissues and, if left untreated, can spread to distant parts of the body through the bloodstream or lymphatic system. It is the most common cancer among women globally. Detecting breast cancer early through regular screenings like mammograms and employing a range of treatments such as surgery, chemotherapy, radiation, and targeted therapies can significantly improve the chances of successful treatment and recovery.

Astrocytoma is a type of brain tumor that originates from astrocytes, the star-shaped cells that make up the supportive tissue of the brain. These tumors can occur in various parts of the brain and spinal cord. Astrocytomas vary in their level of aggressiveness, ranging from benign (non-cancerous) to malignant (cancerous).

Carcinoma of unknown primary (CUP) is a rare disease where cancer cells are found in the body but the place the cancer began, known as the primary site, cannot be determined. Often, the cancer is already advanced by the time it's diagnosed. Early detection and accurate diagnosis of the primary site can aid in targeted treatment.

Colorectal cancer is a type of cancer that begins in the colon or rectum, parts of the large intestine in the digestive system. It typically starts as small, benign clumps of cells called polyps that can, over time, develop into cancers. Early detection through routine screenings can help prevent the progression of colorectal cancer.

Non-Hodgkin lymphoma (NHL) refers to a group of various malignant cancers that develop in the lymph system, which is part of the body's immune system. Unlike Hodgkin lymphoma, NHL types are identified by various unique genetic marker abnormalities. These cancers can originate anywhere in the body and spread to any tissue or organ. It exhibits diverse symptoms and can proceed at varying rates, depending on the type.

Oral cancer refers to any cancerous tissue growth located in the mouth. It may arise as a primary lesion originating in any of the oral tissues, by metastasis from a distant site of origin, or by extension from a neighboring anatomic structure, such as the nasal cavity or the maxillary sinus. Early detection significantly increases the chances of a successful treatment.

Chondrosarcoma is a type of cancer that predominantly affects the cartilage cells. The disease often manifests in the bones of the upper arms, legs, pelvis, or the spine. The condition typically progresses slowly and carries a higher risk factor for adults and older individuals. Treatment commonly includes surgery or radiation therapy.

Ductal Carcinoma In Situ (DCIS) refers to a type of early-stage breast cancer where abnormal cells are found in the lining of the breast milk duct, confined to the area where they started and haven't invaded surrounding tissues. Though non-invasive, it can progress to invasive cancer if untreated.

Familial cancer refers to cancer that occurs significantly more frequently within a family compared to the general population, often due to a genetic predisposition. Despite sharing common environmental factors, these cancers primarily result from inherited gene mutations that are passed on from generation to generation, increasing susceptibility to specific cancer types.

Hodgkin lymphoma, also known as Hodgkin's disease, is a type of blood cancer that originates in the lymphatic system, which is part of the body's immune system. This condition is characterized by the abnormal growth of cells in the lymph nodes, often causing swelling and potentially spreading to other body parts. Typical symptoms include painless swollen lymph nodes, fatigue, and unexplained weight loss.

Anaplastic thyroid cancer is a rare, aggressive type of thyroid cancer characterized by uncontrolled growth of cells in the thyroid, a gland located at the base of the neck. This cancer often grows quickly and spreads to other parts of the body, making it difficult to treat. Despite its severity, it accounts for only about 1-2% of all thyroid cancers.

Epidermoid carcinoma, also known as squamous cell carcinoma, is a type of cancer that primarily originates from the squamous cells found in the skin or the mucous membranes. It's commonly seen on sun-exposed areas like face and hands but can occur in other body parts. It often appears as a scaly, crusty, or warty growth or a non-healing sore. Regular medical checkups are essential for early detection and treatment.

Eyelid cancer refers to a variety of malignancies that affect the eyelid. These are usually skin cancers, which develop from cells lining the eyelid. Its common types include basal cell carcinoma, squamous cell carcinoma, and melanoma. The condition may cause symptoms like a persistent lump, red eye, or irritation. Diagnosis and treatment are crucial to prevent complications such as vision loss.

Fibrosarcoma is a rare type of cancer that originates from fibrous tissue, typically affecting the legs, arms, or trunk. Characterized by the rapid growth of spindle-shaped cells, it is most common in middle-aged adults. With early detection and treatment - often a combination of surgery, radiation, and chemotherapy - the prognosis can be improved.

Leukemia is a group of blood cancer types that primarily affect the bone marrow and white blood cells. It occurs when the body's bone marrow produces an excessive number of abnormal white blood cells, inhibiting the production of red blood cells and platelets, important for proper bodily function. This interferes with the body's ability to fight infections, clot blood, and transport oxygen.

Renal cancer, also known as kidney cancer, is a disease characterized by the abnormal and uncontrollable growth of cells in the kidneys, vital organs that filter waste from the blood. The most common type is renal cell carcinoma. Symptoms may include blood in the urine, back pain, and fatigue. Late detection or diagnosis could lead to the disease spreading to other organs. Treatment varies depending on the stage and may include surgery, radiation, or targeted therapy.

"Squamous cell carcinoma" is a prevalent type of skin cancer that originates from squamous cells. These cells form the outer layer of the skin's epidermis. The condition is commonly caused by prolonged exposure to ultraviolet (UV) radiation from the sun or tanning beds. It often exhibits as a firm, red nodule, or a flat lesion with a scaly, crusty surface. Though primarily appearing on sun-exposed areas, it can occur anywhere on the body. Early diagnosis and treatment are vital in preventing its spread.

Thyroid cancer is a type of malignancy that begins in the thyroid gland, a butterfly-shaped organ at the base of the throat responsible for hormone production. Symptoms often include a lump in the neck, voice changes, difficulty swallowing, or unexplained weight changes. Treatment depends on the stage and type of cancer but can include surgery, radioactive iodine therapy, hormonal therapy, and chemotherapy. Early detection allows for a high survival rate.

Kaposi's sarcoma is a rare type of cancer that causes multiple lesions to form in the skin, oral cavity, lymph nodes, and internal organs. Often associated with individuals having a compromised immune system, such as HIV/AIDS patients, it's triggered by human herpesvirus 8 (HHV-8). Both cutaneous (skin) and visceral (internal organ) forms exist, showcasing symptoms like reddish or purplish patches, nodules, or plaques.

Invasive ductal carcinoma (IDC) is the most common type of breast cancer, accounting for about 80% of all cases. It begins in the milk ducts and spreads to surrounding breast tissue. If undetected or untreated, it can also metastasize to other parts of the body, escalating to a potentially life-threatening condition. It can affect both men and women.

Lobular carcinoma in situ (LCIS) is a condition that indicates the presence of abnormal cells in the lobules of the breast. Although not a cancer itself, LCIS is considered a marker for increased risk of developing breast cancer in the future. It's often detected during a biopsy for another breast condition or during a mammogram.

Lung cancer is a type of malignant disease characterised by the uncontrolled growth of abnormal cells in one or both lungs, specifically in the tissues or air passages. It can be primarily caused by smoking, but non-smokers can get it too due to reasons like exposure to radon gas or secondhand smoke. It's often fatal due to late-stage diagnosis, making early detection crucial.

Melanoma is a type of cancer that originates from the pigment-producing cells, melanocytes. Most commonly found in the skin, it can also occur in the eyes (ocular melanoma) or other parts of the body. Melanoma is notorious for its rapid spread and high mortality rate, particularly if not detected early. Sun exposure is a key risk factor, emphasizing the importance of protection and surveillance.

Neuroblastoma is a rare form of pediatric cancer that originates in the adrenal glands and develops from immature nerve cells found in several areas of the body, including the adrenal glands, chest, abdomen, or spine. It predominantly affects children under the age of five and accounts for a disproportionate number of infant cancer deaths.

Osteosarcoma is a type of cancer that originates in the bones. It most commonly affects adolescents and young adults, but can occur at any age. This aggressive malignant neoplasm leads to abnormal, uncontrollable growth of osteoblasts, the cells responsible for bone formation. It predominantly occurs in long bones like the femur, tibia, and humerus, consequently causing pain and swelling in the affected area.

Ovarian cancer is a type of cancer that begins in the ovaries, the female reproductive glands that produce eggs or ova. It often goes undetected until it has spread within the pelvis and abdomen, making it difficult to treat and often fatal. Symptoms can include abdominal bloating, discomfort, weight loss, and frequent urination. It is the fifth most common cause of cancer-related death among women.

Pancreatic cancer is a type of malignancy that begins in the tissues of the pancreas, an organ residing behind the lower stomach. This organ releases enzymes aiding digestion and hormones managing blood sugar. This form of cancer often shows hardly any early symptoms, spreads swiftly and is mostly detected in advanced stages, making it one of the deadliest types of cancer.

Sarcoma is a type of malignant tumor that arises from transformed cells of mesenchymal (connective tissue) origin. It can occur in various locations in the body, including the bones, muscles, tendons, cartilage, nerves, fat, and blood vessels. Despite being relatively rare, sarcomas are aggressive and often require intense treatment modalities such as surgery, radiation, and chemotherapy.

Acute Myeloid Leukemia (AML) is a rapid-developing type of blood cancer that affects the myeloid line of cells in the bone marrow. Marked by an overproduction of immature white blood cells known as blasts, AML interferes with the production of normal blood cells, leading to anemia, infection, and bleeding complications. Fast diagnosis and treatment are essential due to its aggressive nature.

Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia, a fast-growing cancer of the blood-forming cells in the bone marrow. In APL, immature blood cells called promyelocytes accumulate in the bone marrow, reducing the production of healthy white and red blood cells and platelets. This can lead to fatigue, susceptibility to infections, and increased bleeding.

"B-cell lymphoma" is a type of cancer that forms in B cells, a type of white blood cell that helps the body fight off infections. It is mainly characterized by the abnormal growth and division of B cells, often leading to the development of tumors, commonly in lymph nodes, but possibly anywhere the lymph system exists.

Basal cell carcinoma refers to a type of skin cancer that originates in the basal cells, which produce new skin cells to replace old ones. It often manifests as a waxy or shiny bump, or as a red, scaly patch on skin regularly exposed to the sun. Being the most common type of skin cancer, early detection and treatment can prevent complications.

Bladder cancer is a malignant growth within the bladder, an organ that stores urine. The most common type, transitional cell carcinoma, originates from cells lining the bladder. Risk factors include smoking, chemical exposure, and chronic infections. Symptoms often include hematuria, discomfort during urination, and lower back pain. Early detection and treatment are vital.

Burkitt lymphoma is a type of non-Hodgkin's lymphoma, a fast-growing and aggressive cancer of the lymphatic system. It predominantly affects children and is named after Denis Burkitt, who first identified this disease in African children in 1958. Common symptoms include fever, night sweats, and significant weight loss.

Soft tissue sarcoma is a rare type of cancer arising from the soft tissues like fat, muscle, nerves, fibrous tissues, blood vessels, or deep skin tissues. It can occur in any part of the body, however, it is most commonly found in the arms, legs, chest, or abdomen. Prompt diagnosis and treatment are crucial for managing this condition effectively.

A carcinoid tumor is a rare, slow-growing type of neuroendocrine tumor that primarily originates in the digestive tract or lungs. It often takes years to display symptoms, which may vary depending on the tumor’s location. Though most carcinoid tumors are benign, some can spread to other parts of the body and become malignant. Early diagnosis and proper treatment can manage the tumor effectively.

Cervical cancer is a type of cancer that begins within the cells of the cervix, the lower part of the uterus that connects to the vagina. It occurs when abnormal cells on the cervix grow out of control. Mostly caused by specific strains of the Human Papillomavirus (HPV), it can often be successfully treated when detected early through regular screenings like the Pap test.

Cholangiocarcinoma, commonly known as bile duct cancer, is a rare and aggressive type of cancer that occurs in the tiny, tube-like bile ducts within the liver. These ducts carry bile, a fluid that aids in the digestion of fat, to the gallbladder. This cancer is often hard to diagnose and usually discovered at an advanced stage.

Chronic Lymphocytic Leukemia (CLL) is a type of cancer that initiates in the bone marrow, leading to an overproduction of abnormal, mature lymphocytes (a type of white blood cell). It's identified by gradual progression, typically affecting older adults. Symptoms often include swollen lymph nodes, fatigue, and weight loss.

Chronic Myeloid Leukemia (CML) is a type of cancer that starts in the blood-forming cells of the bone marrow and gradually invades the blood. It's characterized by the excessive growth of white blood cells. CML typically develops slowly, but can shift to a more aggressive phase, known as blast crisis, if untreated.

Endometrial cancer is a type of cancer that starts in the inner lining of the uterus, known as the endometrium. It is the most common form of uterine cancer and is typically diagnosed in postmenopausal women. Symptoms may include abnormal vaginal bleeding, pelvic pain, and pain during intercourse. Early detection is crucial for successful treatment.

Esophageal cancer is a type of malignancy that originates in the esophagus, the long, hollow tube that connects your throat to your stomach. It generally starts in the cells lining the esophagus and can occur anywhere along the esophagus. The disease is often symptomatic with difficulty swallowing, weight loss, or chest discomfort. The two primary types are squamous cell carcinoma and adenocarcinoma.

"Gallbladder cancer is a relatively rare form of cancer that originates in the gallbladder, an organ located under the liver that stores bile. This disease often goes undetected due to its hidden location and lack of early symptoms. The specific cause of gallbladder cancer is unknown, but some factors like gallstones, bile duct abnormalities, and certain liver diseases may increase its risk."

Gastric cancer, also known as stomach cancer, is a disease characterized by abnormal and uncontrolled growth of cells in the stomach lining, forming a mass or tumor. Its symptoms include indigestion, unintended weight loss, stomach pain, bloating, and nausea. Risk factors include Helicobacter pylori infection, smoking, certain dietary factors, and genetic conditions.

Glioblastoma is a malignant, aggressive type of brain cancer that arises from star-shaped cells (astrocytes) forming the supportive tissue of the brain. Known for its fast growth and spread, it is the most lethal of brain cancers. Symptoms usually include headaches, seizures, and neurological deficits. Despite available treatments like surgery, radiation, and chemotherapy, prognosis remains poor.

"Glioma" is a type of tumor that occurs in the brain and spinal cord. It begins in the glial cells, which provide support and protection for neurons in the brain. Gliomas can set in across different forms and severity, ranging from benign to highly malignant. Symptoms typically vary and depend on the tumor's location and size.

Inflammatory Breast Cancer (IBC) is an aggressive and uncommon type of breast cancer characterized by extensive inflammation and redness in the breast. It progresses rapidly, often making the breast swollen, tender, and appearing infected. IBC accounts for 1-5% of all breast cancer cases, demanding early diagnosis and prompt treatment to optimize patient outcomes.